Music in Dubrovnik advanced with the support of the most affluent nobility. The first musical groups were formed to perform concerts in celebration of the city's patron saint, Blaise (locally Saint Vlaho). For these performances only the most talented musicians were selected.
As the number of musicians in the Republic increased, the Senate decided to introduce qualified professors who could teach music to the youth. Apart from teaching, these professors played in the orchestra Knez's Music (Croatian: Kneževe glazbe). Musical influence during this time mostly came from the Italian city states, so the professors during this time were mostly from Italy. Young musicians extended their musical education most often in the cities of Naples and Rome.
In modern times, an orchestra was formed August 25, 1925 under the name Dubrovnik Philharmonic Orchestra. The first symphony concert was held in the Marin Drži? Theatre under the Polish conductor Tadeusz Sygietynski, then the conductor of the Warsaw opera company. Reviews of the performance were good, and the activities of the orchestra were soon financed by the local government.
Over the years the orchestra changed its name several times. In 1946 it took on the name Dubrovnik City Orchestra. In 1992, it began to work closely with the Dubrovnik Summer Games and changed its name to the Dubrovnik Festival Orchestra. The current name was adopted in 1995.
Over the years many well-known conductors and performers have played with the orchestra: Lovro Mata?i?, Zubin Mehta, Kiril Kondrašin, Ernst Marzendorfer, Henryk Szeryng, Mstislav Rostropovi?, Antonio Janigro, Kyril Kondrašin, Yehudi Menuhin, David Oistrach, Sviatoslav Richter and others.